Ligandability Assessment of Human Glutathione Transferase M1-1 Using Pesticides as Chemical Probes

Glutathione transferases (GSTs; EC 2.5.1.18) form a group of multifunctional enzymes that are involved in phase II of the cellular detoxification mechanism and are associated with increased susceptibility to cancer development and resistance to anticancer drugs. The present study aims to evaluate th...

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Bibliographic Details
Main Authors: Charoutioun S. Bodourian, Nirmal Poudel, Anastassios C. Papageorgiou, Mariana Antoniadi, Nikolaos D. Georgakis, Hiroshi Abe, Nikolaos E. Labrou
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/7/3606