Abelson tyrosine-protein kinase 2 regulates myoblast proliferation and controls muscle fiber length

Muscle fiber length is nearly uniform within a muscle but widely different among different muscles. We show that Abelson tyrosine-protein kinase 2 (Abl2) has a key role in regulating myofiber length, as a loss of Abl2 leads to excessively long myofibers in the diaphragm, intercostal and levator auri...

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Bibliographic Details
Main Authors: Jennifer K Lee, Peter T Hallock, Steven J Burden
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/29905