Prediction of smoking by multiplex bisulfite PCR with long amplicons considering allele-specific effects on DNA methylation

Prediction of smoking by multiplex bisulfite PCR with long amplicons considering allele-specific effects on DNA methylation

Abstract Background Methylation of DNA is associated with a variety of biological processes. With whole-genome studies of DNA methylation, it became possible to determine a set of genomic sites where DNA methylation is associated with a specific phenotype. A method is needed that allows detailed fol...

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Bibliographic Details
Main Authors: Nikolay Kondratyev, Arkady Golov, Margarita Alfimova, Tatiana Lezheiko, Vera Golimbet
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Clinical Epigenetics
Subjects:
Allele-specific methylation
Clinical sequencing
DNA methylation
Single-molecule sequencing
Smoking
Schizophrenia
Online Access:http://link.springer.com/article/10.1186/s13148-018-0565-1

Internet

http://link.springer.com/article/10.1186/s13148-018-0565-1

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