A single cell transcriptional roadmap of human pacemaker cell differentiation

A single cell transcriptional roadmap of human pacemaker cell differentiation

Each heartbeat is triggered by the sinoatrial node (SAN), the primary pacemaker of the heart. Studies in animal models have revealed that pacemaker cells share a common progenitor with the (pro)epicardium, and that the pacemaker cardiomyocytes further diversify into ‘transitional’, ‘tail’, and ‘head...

Full description

Bibliographic Details
Main Authors: Alexandra Wiesinger, Jiuru Li, Lianne Fokkert, Priscilla Bakker, Arie O Verkerk, Vincent M Christoffels, Gerard JJ Boink, Harsha D Devalla
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-10-01
Series:eLife
Subjects:
iPSC
pacemaker cell
trajectory inference
cardiac differentiation
sinoatrial node
scRNA-seq
Online Access:https://elifesciences.org/articles/76781

Internet

https://elifesciences.org/articles/76781

Similar Items