EphH, a unique epoxide hydrolase encoded by Rv3338 is involved in the survival of Mycobacterium tuberculosis under in vitro stress and vacuolar pH-induced changes

IntroductionMycobacterium tuberculosis (Mtb), one of the deadliest human pathogen, has evolved with different strategies of survival inside the host, leading to a chronic state of infection. Phagosomally residing Mtb encounters a variety of stresses, including increasing acidic pH. To better underst...

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Bibliographic Details
Main Authors: Tanu Garg, Swetarka Das, Shriya Singh, Mohmmad Imran, Atri Mukhopadhyay, Umesh D. Gupta, Sidharth Chopra, Arunava Dasgupta
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1092131/full