Role of endothelin in cardiovascular disease

Endothelins are a family of peptides, which comprises endothelin-1 (ET-1), endothelin-2 (ET-2) and endothelin-3 (ET-3), each containing 21 amino-acids. ET-1 is a peptide secreted mostly by vascular endothelial cells, the predominant isoform expressed in vasculature and the most potent vasoconstricto...

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Bibliographic Details
Main Authors: Alexei V Agapitov, William G Haynes
Format: Article
Language:English
Published: SAGE Publications 2002-03-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2002.001