Autophagy Signaling by Neural-Induced Human Adipose Tissue-Derived Stem Cell-Conditioned Medium during Rotenone-Induced Toxicity in SH-SY5Y Cells

Autophagy Signaling by Neural-Induced Human Adipose Tissue-Derived Stem Cell-Conditioned Medium during Rotenone-Induced Toxicity in SH-SY5Y Cells

Rotenone (ROT) inhibits mitochondrial complex I, leading to reactive oxygen species formation, which causes neurodegeneration and alpha-synuclein (α-syn) aggregation and, consequently, Parkinson’s disease. We previously found that a neurogenic differentiated human adipose tissue-derived stem cell-co...

Full description

Bibliographic Details
Main Authors: Mahesh Ramalingam, Han-Seong Jeong, Jinsu Hwang, Hyong-Ho Cho, Byeong C. Kim, Eungpil Kim, Sujeong Jang
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
Parkinson’s disease
LC3B
rotenone
mTOR
mesenchymal stem cells
Online Access:https://www.mdpi.com/1422-0067/23/8/4193

Internet

https://www.mdpi.com/1422-0067/23/8/4193

Similar Items