Ovariectomy results in variable changes in nociception, mood and depression in adult female rats.

Decline in the ovarian hormones with menopause may influence somatosensory, cognitive, and affective processing. The present study investigated whether hormonal depletion alters the nociceptive, depressive-like and learning behaviors in experimental rats after ovariectomy (OVX), a common method to d...

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Bibliographic Details
Main Authors: Li-Hong Li, Zhe-Chen Wang, Jin Yu, Yu-Qiu Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094312&type=printable