Prediction model construction of mouse stem cell pluripotency using CpG and non-CpG DNA methylation markers

Abstract Background Genome-wide studies of DNA methylation across the epigenetic landscape provide insights into the heterogeneity of pluripotent embryonic stem cells (ESCs). Differentiating into embryonic somatic and germ cells, ESCs exhibit varying degrees of pluripotency, and epigenetic changes o...

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Bibliographic Details
Main Authors: Soobok Joe, Hojung Nam
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-020-3448-3