A continuous-time stochastic Boolean model provides a quantitative description of the budding yeast cell cycle

Abstract The cell division cycle is regulated by a complex network of interacting genes and proteins. The control system has been modeled in many ways, from qualitative Boolean switching-networks to quantitative differential equations and highly detailed stochastic simulations. Here we develop a con...

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Bibliographic Details
Main Authors: Teeraphan Laomettachit, Pavel Kraikivski, John J. Tyson
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24302-6