Transforming growth factor beta activity in urine of patients with type 2 diabetes and diabetic nephropathy

Transforming growth factor beta activity in urine of patients with type 2 diabetes and diabetic nephropathy

Diabetic nephropathy (DN) is characterized structurally by progressive mesangial deposition of extracellular matrix (ECM). Transforming growth factor-ß (TGF-ß) is considered to be one of the major cytokines involved in the regulation of ECM synthesis and degradation. Several studies suggest that an...

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Bibliographic Details
Main Authors: Rivarola E.W.R., Moyses-Neto M., Dantas M., da-Silva C.G., Volpini R., Coimbra T.M.
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1999-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
TGF-ß urinary excretion
type 2 diabetes
proteinuria
diabetic nephropathy
extracellular matrix
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001200011

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001200011

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