Transforming growth factor beta activity in urine of patients with type 2 diabetes and diabetic nephropathy
Diabetic nephropathy (DN) is characterized structurally by progressive mesangial deposition of extracellular matrix (ECM). Transforming growth factor-ß (TGF-ß) is considered to be one of the major cytokines involved in the regulation of ECM synthesis and degradation. Several studies suggest that an...
Main Authors: | Rivarola E.W.R., Moyses-Neto M., Dantas M., da-Silva C.G., Volpini R., Coimbra T.M. |
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Format: | Article |
Language: | English |
Published: |
Associação Brasileira de Divulgação Científica
1999-01-01
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Series: | Brazilian Journal of Medical and Biological Research |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001200011 |
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