Stability of Norwalk virus capsid protein interfaces evaluated by in-silico nanoindentation

Norwalk virus causes severe gastroenteritis for which there is currently no specific anti-viral therapy. A stage of the infection process is uncoating of the protein capsid to expose the viral genome and allow for viral replication. A mechanical characterization of the Norwalk virus may provide impo...

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Bibliographic Details
Main Authors: Kevin J Boyd, Prakhar eBansal, Jun eFeng, Eric R May
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00103/full