Pharmacogenomics of Vincristine-Induced Peripheral Neuropathy in Children with Cancer: A Systematic Review and Meta-Analysis

Pharmacogenomics of Vincristine-Induced Peripheral Neuropathy in Children with Cancer: A Systematic Review and Meta-Analysis

Vincristine-induced peripheral neuropathy (VIPN) is a debilitating side-effect of vincristine. It remains a challenge to predict which patients will suffer from VIPN. Pharmacogenomics may explain an individuals’ susceptibility to side-effects. In this systematic review and meta-analysis, we describe...

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Bibliographic Details
Main Authors: Aniek Uittenboogaard, Céline L. G. Neutel, Johannes C. F. Ket, Festus Njuguna, Alwin D. R. Huitema, Gertjan J. L. Kaspers, Mirjam E. van de Velde
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
vincristine
vincristine-induced peripheral neuropathy
pediatric oncology
pharmacogenomics
meta-analysis
CYP3A5
Online Access:https://www.mdpi.com/2072-6694/14/3/612

Internet

https://www.mdpi.com/2072-6694/14/3/612

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