Assessing immunogenicity and protectiveness of the vaccinia virus LIVP-GFP in three laboratory animal models

Assessing immunogenicity and protectiveness of the vaccinia virus LIVP-GFP in three laboratory animal models

Smallpox eradication and lack of adequate animal model for smallpox infection underlies a necessity to assess immunogenic and protective properties of genetic engineering-created live attenuated smallpox vaccines in several animal models of orthopoxviral infections. Here we compared immunogenic and...

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Bibliographic Details
Main Authors: S. N. Shchelkunov, A. A. Sergeev, S. N. Yakubitskyi, K. A. Titova, S. A. Pyankov
Format: Article
Language:Russian
Published: Sankt-Peterburg : NIIÈM imeni Pastera 2022-01-01
Series:Инфекция и иммунитет
Subjects:
vaccinia virus
attenuation
immune response
antibodies
protectiveness
orthopoxviruses
Online Access:https://www.iimmun.ru/iimm/article/view/1668

Internet

https://www.iimmun.ru/iimm/article/view/1668

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