Naringenin ameliorates myocardial injury in STZ-induced diabetic mice by reducing oxidative stress, inflammation and apoptosis via regulating the Nrf2 and NF-κB signaling pathways

Naringenin ameliorates myocardial injury in STZ-induced diabetic mice by reducing oxidative stress, inflammation and apoptosis via regulating the Nrf2 and NF-κB signaling pathways

Diabetes-induced myocardial damage leads to diabetic cardiomyopathy and is closely associated with the generation of oxidative stress and inflammation. Naringenin (NG) exhibits antioxidant and anti-inflammatory effects. However, whether NG has cardioprotective effects against diabetic cardiomyopathy...

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Bibliographic Details
Main Authors: Yongpeng He, Shuaiqi Wang, Hao Sun, Yan Li, Jian Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
naringenin
inflammation
oxidative stress
diabetic cardiomyopathy
Nrf2
NF-κB
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.946766/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2022.946766/full

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