Overexpression of ERAP2N in Human Trophoblast Cells Promotes Cell Death

Overexpression of ERAP2N in Human Trophoblast Cells Promotes Cell Death

The genes involved in implantation and placentation are tightly regulated to ensure a healthy pregnancy. The endoplasmic reticulum aminopeptidase 2 (ERAP2) gene is associated with preeclampsia (PE). Our studies have determined that an isoform of ERAP2-arginine (N), expressed in trophoblast cells (TC...

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Bibliographic Details
Main Authors: Kristen Lospinoso, Mikhail Dozmorov, Nadine El Fawal, Rhea Raghu, Wook-Jin Chae, Eun D. Lee
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
ERAP2
trophoblast cells
pregnancy
pre-eclampsia
RNA sequencing
differentially expressed genes
Online Access:https://www.mdpi.com/1422-0067/22/16/8585

Internet

https://www.mdpi.com/1422-0067/22/16/8585

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