Castanea mollissima shell polyphenols regulate JAK2 and PPARγ expression to suppress inflammation and lipid accumulation by inhibiting M1 macrophages polarization

Castanea mollissima shell polyphenols regulate JAK2 and PPARγ expression to suppress inflammation and lipid accumulation by inhibiting M1 macrophages polarization

Castanea mollissima shells are a by-product of Chinese chestnut processing and contain many polyphenols. Macrophage polarization plays an important role in the progression of atherosclerosis (AS). We investigated the action of Castanea mollissima shell polyphenols (CSPs), with proanthocyanidin C1 an...

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Bibliographic Details
Main Authors: Suwen Liu, Zhang Lu, Chang Liu, Xuedong Chang, Buhailiqiemu Apudureheman, Shiguo Chen, Xingqian Ye
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Journal of Functional Foods
Subjects:
Castanea mollissima shell polyphenols
Macrophage polarization
Inflammation
Cholesterol
Regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464622001165

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http://www.sciencedirect.com/science/article/pii/S1756464622001165

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