Comparative Genomic Analysis of <italic toggle="yes">Mycobacteriaceae</italic> Reveals Horizontal Gene Transfer-Mediated Evolution of the CRISPR-Cas System in the <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Complex

Comparative Genomic Analysis of <italic toggle="yes">Mycobacteriaceae</italic> Reveals Horizontal Gene Transfer-Mediated Evolution of the CRISPR-Cas System in the <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Complex

ABSTRACT Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) genes are conserved genetic elements in many prokaryotes, including Mycobacterium tuberculosis, the causative agent of tuberculosis. Although knowledge of CRISPR locus variability has been utilize...

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Bibliographic Details
Main Authors: Anoop Singh, Mohita Gaur, Vishal Sharma, Palak Khanna, Ankur Bothra, Asani Bhaduri, Anupam Kumar Mondal, Debasis Dash, Yogendra Singh, Richa Misra
Format: Article
Language:English
Published: American Society for Microbiology 2021-02-01
Series:mSystems
Subjects:
CRISPR-Cas system
Mycobacterium
Mycobacterium tuberculosis
Mycobacterium canettii
horizontal gene transfer
IS6110
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00934-20

Internet

https://journals.asm.org/doi/10.1128/mSystems.00934-20

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