Patient-derived xenografts of low-grade B-cell lymphomas demonstrate roles of the tumor microenvironment

Abstract: To discern features of non-Hodgkin lymphomas (NHL) that are autonomous from those that are shaped by the tumor environment (TE), we used patient-derived xenografts (PDX) to probe the effects on neoplastic cells of manipulating the TE. Properties of neoplastic cells that are often considere...

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Bibliographic Details
Main Authors: W. Richard Burack, Janice M. Spence, John P. Spence, Stephen A. Spence, Philip J. Rock, Gautam N. Shenoy, Leonard D. Shultz, Richard B. Bankert, Steven H. Bernstein
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952920302433