Copy number alterations analysis of primary tumor tissue and circulating tumor cells from patients with early-stage triple negative breast cancer

Copy number alterations analysis of primary tumor tissue and circulating tumor cells from patients with early-stage triple negative breast cancer

Abstract Triple negative breast cancer (TNBC) is characterized by clinical aggressiveness, lack of recognized target therapy, and a dismal patient prognosis. Several studies addressed genomic changes occurring during neoadjuvant chemotherapy (NAC) focusing on somatic variants, but without including...

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Bibliographic Details
Main Authors: Marco Silvestri, Matteo Dugo, Marta Vismara, Loris De Cecco, Davide Lanzoni, Andrea Vingiani, Secondo Folli, Maria Carmen De Santis, Filippo de Braud, Giancarlo Pruneri, Serena Di Cosimo, Vera Cappelletti
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-05502-6

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https://doi.org/10.1038/s41598-022-05502-6

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