Tandem Use of OvMANE1 and Ov-16 ELISA Tests Increases the Sensitivity for the Diagnosis of Human Onchocerciasis

Tandem Use of OvMANE1 and Ov-16 ELISA Tests Increases the Sensitivity for the Diagnosis of Human Onchocerciasis

The current serological test for human onchocerciasis relies on IgG4 reactivity against the parasite Ov-16 antigen, with reported sensitivities of only 60–80%. As control programs move from control to elimination, it is imperative to identify novel molecules that could improve the serodiagnosis reli...

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Bibliographic Details
Main Authors: Cabirou Mounchili Shintouo, Stephen Mbigha Ghogomu, Robert Adamu Shey, An Hotterbeekx, Emel Yagmur, Tony Mets, Luc Vanhamme, Robert Colebunders, Jacob Souopgui, Rose Njemini
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Life
Subjects:
<i>Onchocerca volvulus</i>
OvMANE1
Ov-16
ELISA
diagnostic
sensitivity
Online Access:https://www.mdpi.com/2075-1729/11/12/1284

Internet

https://www.mdpi.com/2075-1729/11/12/1284

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