Umbelliferone attenuates cisplatin‐induced acute kidney injury by inhibiting oxidative stress and inflammation via NRF2

Umbelliferone attenuates cisplatin‐induced acute kidney injury by inhibiting oxidative stress and inflammation via NRF2

Abstract In this study, we investigated the nephroprotective effects of Umbelliferone (UMB) against cisplatin‐induced acute kidney injury (AKI). C57BL/6J mice were treated with cisplatin via a single intraperitoneal injection (25 mg/kg) with or without UMB (40 mg/kg/day) by gavage. Renal function, a...

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Bibliographic Details
Main Authors: Zhenle Yang, Ruofei Ning, Qianying Liu, Ruixian Zang, Suwen Liu, Shuzhen Sun
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Physiological Reports
Subjects:
cisplatin‐induced AKI
inflammation
NRF2
oxidative stress
UMB
Online Access:https://doi.org/10.14814/phy2.15879

Internet

https://doi.org/10.14814/phy2.15879

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