Mechanisms of Chemotherapy Resistance in Triple-Negative Breast Cancer—How We Can Rise to the Challenge

Mechanisms of Chemotherapy Resistance in Triple-Negative Breast Cancer—How We Can Rise to the Challenge

Triple-negative (TNBC) is the most lethal subtype of breast cancer owing to high heterogeneity, aggressive nature, and lack of treatment options. Chemotherapy remains the standard of care for TNBC treatment, but unfortunately, patients frequently develop resistance. Accordingly, in recent years, tre...

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Bibliographic Details
Main Authors: Milica Nedeljković, Ana Damjanović
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
triple-negative breast cancer
chemoresistance
ABC transporters
cancer stem cells
signaling pathways
hypoxia
apoptosis
receptor tyrosine kinases
microRNA
molecular subtypes
Online Access:https://www.mdpi.com/2073-4409/8/9/957

Internet

https://www.mdpi.com/2073-4409/8/9/957

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