OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes

OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes

Olfactory receptors (ORs) are the largest protein superfamily in mammals. Certain ORs are ectopically expressed in extranasal tissues and regulate cell type-specific signal transduction pathways. OR2AT4 is ectopically expressed in skin cells and promotes wound healing and hair growth. As the capacit...

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Bibliographic Details
Main Authors: Ji-Sun Kim, Ha Lim Lee, Ji Hyun Jeong, Ye Eun Yoon, In-Ryeong Lee, Ji Min Kim, Chunyan Wu, Sung-Joon Lee
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Antioxidants
Subjects:
olfactory receptor
OR2AT4
sandalore
senescence
human keratinocytes
CaMKKβ/AMPK/mTORC1/autophagy signaling
Online Access:https://www.mdpi.com/2076-3921/11/11/2180

Internet

https://www.mdpi.com/2076-3921/11/11/2180

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