Mechanosensitive Pannexin 1 Activity Is Modulated by Stomatin in Human Red Blood Cells

Mechanosensitive Pannexin 1 Activity Is Modulated by Stomatin in Human Red Blood Cells

Pannexin 1 (PANX1) was proposed to drive ATP release from red blood cells (RBCs) in response to stress conditions. Stomatin, a membrane protein regulating mechanosensitive channels, has been proposed to modulate PANX1 activity in non-erythroid cells. To determine whether stomatin modulates PANX1 act...

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Bibliographic Details
Main Authors: Sarah Rougé, Sandrine Genetet, Maria Florencia Leal Denis, Michael Dussiot, Pablo Julio Schwarzbaum, Mariano Anibal Ostuni, Isabelle Mouro-Chanteloup
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
erythrocyte
ATP release
pannexin activity
stomatin
overhydrated hereditary stomatocytosis
Online Access:https://www.mdpi.com/1422-0067/23/16/9401

Internet

https://www.mdpi.com/1422-0067/23/16/9401

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