SAC1 regulates autophagosomal phosphatidylinositol-4-phosphate for xenophagy-directed bacterial clearance

Summary: Phosphoinositides are important molecules in lipid signaling, membrane identity, and trafficking that are spatiotemporally controlled by factors from both mammalian cells and intracellular pathogens. Here, using small interfering RNA (siRNA) directed against phosphoinositide kinases and pho...

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Bibliographic Details
Main Authors: Kai Liu, Lingjia Kong, Daniel B. Graham, Kimberly L. Carey, Ramnik J. Xavier
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721008512