Pathogenic bacteria experience pervasive RNA polymerase backtracking during infection

ABSTRACTPathogenic bacteria and their eukaryotic hosts are in a constant arms race. Hosts have numerous defense mechanisms, including some that cause DNA damage. How these host defense mechanisms impact molecular transactions along the bacterial chromosome during infection is unclear. This is partia...

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Bibliographic Details
Main Authors: Kaitlyn R. Browning, Houra Merrikh
Format: Article
Language:English
Published: American Society for Microbiology 2024-01-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.02737-23