The Synthesis and Base-Induced Breakdown of Triaryl 1,4-Oxathiins—An Experimental and DFT Study

The Synthesis and Base-Induced Breakdown of Triaryl 1,4-Oxathiins—An Experimental and DFT Study

1,4-Oxathiins are valued for a breadth of bioactivities and are known commercial fungicides. This article explores a novel preparation of 2,3,6-trisubstituted 1,4-oxathiin-S,S-dioxides via the reaction of benzyl 1-alkynyl sulfones and aryl aldehydes under basic conditions. A total of 20 examples pos...

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Bibliographic Details
Main Authors: Eric A. Nicol, Matthew Sing, Lilly U. Luu, Erwin J. Remigio, Michelle B. Mills, Adrian L. Schwan
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Molecules
Subjects:
oxathiin
sulfone
cyclization
computational chemistry
DFT
α-sulfonyl anion
Online Access:https://www.mdpi.com/1420-3049/28/17/6180

Internet

https://www.mdpi.com/1420-3049/28/17/6180

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