High-Dose Thiamine Supplementation in Older Patients With Heart Failure: A Pilot Randomized Controlled Crossover Trial (THIAMINE-HF)

High-Dose Thiamine Supplementation in Older Patients With Heart Failure: A Pilot Randomized Controlled Crossover Trial (THIAMINE-HF)

Background: Thiamine supplementation may improve cardiac function in older adults with heart failure (HF). Our objectives were to determine the following: (i) the feasibility of conducting a large trial of thiamine supplementation in HF; and (ii) the effects of thiamine on clinical outcomes. Methods...

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Bibliographic Details
Main Authors: Eric K.C. Wong, MD, Justin Y. Lee, BScPhm, MD, PhD, Justin Chow, MD, Patricia Power, BSc, MSc, Laura Jin, BSc, MSc, Darryl P. Leong, MBBS, MPH, M.Biostat, PhD, Lawrence Mbuagbaw, MD, MPH, PhD, Sabina Keen, MD, Haroon Yousuf, MD, MHSc, Christopher Patterson, MD, Sharon Straus, MD, MSc, Catherine Demers, MD, MSc
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:CJC Open
Online Access:http://www.sciencedirect.com/science/article/pii/S2589790X22000324

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http://www.sciencedirect.com/science/article/pii/S2589790X22000324

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