Single‐Nucleus RNA Sequencing and Spatial Transcriptomics Reveal the Immunological Microenvironment of Cervical Squamous Cell Carcinoma

Single‐Nucleus RNA Sequencing and Spatial Transcriptomics Reveal the Immunological Microenvironment of Cervical Squamous Cell Carcinoma

Abstract The effective treatment of advanced cervical cancer remains challenging. Herein, single‐nucleus RNA sequencing (snRNA‐seq) and SpaTial enhanced resolution omics‐sequencing (Stereo‐seq) are used to investigate the immunological microenvironment of cervical squamous cell carcinoma (CSCC). The...

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Bibliographic Details
Main Authors: Zhihua Ou, Shitong Lin, Jiaying Qiu, Wencheng Ding, Peidi Ren, Dongsheng Chen, Jiaxuan Wang, Yihan Tong, Di Wu, Ao Chen, Yuan Deng, Mengnan Cheng, Ting Peng, Haorong Lu, Huanming Yang, Jian Wang, Xin Jin, Ding Ma, Xun Xu, Yanzhou Wang, Junhua Li, Peng Wu
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Advanced Science
Subjects:
cancer‐associated fibroblasts
cervical cancer
single‐nucleus RNA sequencing
spatial transcriptomics
tumor microenvironment
Online Access:https://doi.org/10.1002/advs.202203040

Internet

https://doi.org/10.1002/advs.202203040

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