Non-canonicaly recruited TCRαβCD8αα IELs recognize microbial antigens
Abstract In the gut, various subsets of intraepithelial T cells (IELs) respond to self or non-self-antigens derived from the body, diet, commensal and pathogenic microbiota. Dominant subset of IELs in the small intestine are TCRαβCD8αα+ cells, which are derived from immature thymocytes that express...
Główni autorzy: | , , , , , , , |
---|---|
Format: | Artykuł |
Język: | English |
Wydane: |
Nature Portfolio
2018-07-01
|
Seria: | Scientific Reports |
Dostęp online: | https://doi.org/10.1038/s41598-018-29073-7 |