Synthesis and Anticancer Activity of 1,3,4-Thiadiazoles with 3-Methoxyphenyl Substituent

Synthesis and Anticancer Activity of 1,3,4-Thiadiazoles with 3-Methoxyphenyl Substituent

Based on the results of previous work, we designed and synthesized 1,3,4-thiadiazole derivatives. The cytotoxic activity of the obtained compounds was then determined in biological studies using MCF-7 and MDA-MB-231 breast cancer cells and a normal cell line (fibroblasts). The results showed that al...

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Bibliographic Details
Main Authors: Sara Janowska, Dmytro Khylyuk, Agnieszka Gornowicz, Anna Bielawska, Michał Janowski, Robert Czarnomysy, Krzysztof Bielawski, Monika Wujec
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
thiosemicarbazides
1,3,4-thiadiazoles
anticancer activity
breast cancer
mechanism of action
Online Access:https://www.mdpi.com/1420-3049/27/20/6977

Internet

https://www.mdpi.com/1420-3049/27/20/6977

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