Extrahepatic Vitamin K-Dependent Gla-Proteins–Potential Cardiometabolic Biomarkers

Extrahepatic Vitamin K-Dependent Gla-Proteins–Potential Cardiometabolic Biomarkers

One mechanism to regulate pathological vascular calcification (VC) is its active inhibition. Loss or inactivation of endogenic inhibitors is a major inductor of VC. Such inhibitors are proteins rich in gamma-glutamyl residues (Gla-proteins), whose function strongly depends on vitamin K. The current...

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Bibliographic Details
Main Authors: Bistra Galunska, Yoto Yotov, Miglena Nikolova, Atanas Angelov
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
vascular calcification
cardiometabolic
Gla-proteins
osteocalcin
matrix Gla-protein
Gla-rich protein
Online Access:https://www.mdpi.com/1422-0067/25/6/3517

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https://www.mdpi.com/1422-0067/25/6/3517

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