The lipolysis inhibitor acipimox reverses the cardiac phenotype induced by electronic cigarettes

Abstract Electronic cigarettes (e-cigarettes) are a prevalent alternative to conventional nicotine cigarettes among smokers and people who have never smoked. Increased concentrations of serum free fatty acids (FFAs) are crucial in generating lipotoxicity. We studied the effects of acipimox, an antil...

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Bibliographic Details
Main Authors: Jorge Espinoza-Derout, Jose Mari Luis Arambulo, William Ramirez-Trillo, Juan Carlos Rivera, Kamrul M. Hasan, Candice J. Lao, Maria C. Jordan, Xuesi M. Shao, Kenneth P. Roos, Amiya P. Sinha-Hikim, Theodore C. Friedman
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-44082-x