Microwave-Assisted Synthesis and Antimicrobial Evaluation of Novel Spiroisoquinoline and Spiropyrido[4,3-d]pyrimidine Derivatives

Microwave-Assisted Synthesis and Antimicrobial Evaluation of Novel Spiroisoquinoline and Spiropyrido[4,3-d]pyrimidine Derivatives

Bromination of N-substituted homophthalimides and tetrahydropyrido[4,3-d]- pyrimidine-5,7-diones produces 4,4-dibromohomophthalimide and 8,8-dibromo-tetrahydropyrido[4,3-d]pyrimidine-5,7-dione derivatives, respectively, that can be used as precursors for spiro derivatives. The dibromo derivatives re...

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Bibliographic Details
Main Authors: Rasha M. Faty, Mohamed S. Rashed, Mohamed M. Youssef
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:Molecules
Subjects:
bromination
homophthalimide
pyrido[4,3-d]pyrimidine
spiro compounds
microwave
antimicrobial
Online Access:http://www.mdpi.com/1420-3049/20/2/1842

Internet

http://www.mdpi.com/1420-3049/20/2/1842

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