Sex-dependent development of Kras-induced anal squamous cell carcinoma in mice.

Anal squamous cell carcinoma (SCC) will be diagnosed in an estimated 9,080 adults in the United States this year, and rates have been rising over the last several decades. Most people that develop anal SCC have associated human papillomavirus (HPV) infection (~85-95%), with approximately 5-15% of an...

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Bibliographic Details
Main Authors: Morgan T Walcheck, Kristina A Matkowskyj, Anne Turco, Simon Blaine-Sauer, Manabu Nukaya, Jessica Noel, Oline K Ronnekleiv, Sean M Ronnekleiv-Kelly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0259245