Integration of histone modification-based risk signature with drug sensitivity analysis reveals novel therapeutic strategies for lower-grade glioma

Integration of histone modification-based risk signature with drug sensitivity analysis reveals novel therapeutic strategies for lower-grade glioma

BackgroundLower-grade glioma (LGG) exhibits significant heterogeneity in clinical outcomes, and current prognostic markers have limited predictive value. Despite the growing recognition of histone modifications in tumor progression, their role in LGG remains poorly understood. This study aimed to de...

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Bibliographic Details
Main Authors: Jingyuan Wang, Shuai Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
lower-grade glioma
histone modification
risk signature
drug sensitivity
prognosis
machine learning
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1523779/full

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https://www.frontiersin.org/articles/10.3389/fphar.2024.1523779/full

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