Interferon gamma-inducible protein 16 (IFI16) and anti-IFI16 antibodies in primary Sjögren’s syndrome: findings in serum and minor salivary glands

Interferon gamma-inducible protein 16 (IFI16) and anti-IFI16 antibodies in primary Sjögren’s syndrome: findings in serum and minor salivary glands

The interferon (IFN) signature, namely the overexpression of IFN-inducible genes is a crucial aspect in the pathogenesis of primary Sjögren’s syndrome (pSS). The IFN-inducible IFI16 protein, normally expressed in cell nuclei, may be overexpressed, mislocalized in the cytoplasm and secreted in the ex...

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Bibliographic Details
Main Authors: A. Alunno, V. Caneparo, F. Carubbi, O. Bistoni, S. Caterbi, M. Gariglio, E. Bartoloni, S. Landolfo, R. Gerli
Format: Article
Language:English
Published: PAGEPress Publications 2016-02-01
Series:Reumatismo
Subjects:
Sjögren’s syndrome
interferons
IFI16.
Online Access:http://www.reumatismo.org/index.php/reuma/article/view/839

Internet

http://www.reumatismo.org/index.php/reuma/article/view/839

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