Resistance Patterns Associated with HCV NS5A Inhibitors Provide Limited Insight into Drug Binding

Direct-acting antivirals (DAAs) have significantly improved the treatment of infection with the hepatitis C virus. A promising class of novel antiviral agents targets the HCV NS5A protein. The high potency and broad genotypic coverage are favorable properties. NS5A inhibitors are currently assessed...

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Bibliographic Details
Main Authors: Moheshwarnath Issur, Matthias Götte
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/6/11/4227