TNF Signaling Is Required for Castration-Induced Vascular Damage Preceding Prostate Cancer Regression

The mainstay treatment for locally advanced, recurrent, or metastatic prostate cancer (PrCa) is androgen deprivation therapy (ADT). ADT causes prostate cancers to shrink in volume, or regress, by inducing epithelial tumor cell apoptosis. In normal, non-neoplastic murine prostate, androgen deprivatio...

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Bibliographic Details
Main Authors: John J. Krolewski, Shalini Singh, Kai Sha, Neha Jaiswal, Steven G. Turowski, Chunliu Pan, Laurie J. Rich, Mukund Seshadri, Kent L. Nastiuk
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/24/6020