Dissecting the Crosstalk between NRF2 Signaling and Metabolic Processes in Cancer
The transcription factor NRF2 (nuclear factor-erythroid 2 p45-related factor 2 or <i>NFE2L2</i>) plays a critical role in response to cellular stress. Following an oxidative insult, NRF2 orchestrates an antioxidant program, leading to increased glutathione levels and decreased reactive o...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-10-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/12/10/3023 |