Accelerated Dereplication of Natural Products, Supported by Reference Libraries

Accelerated Dereplication of Natural Products, Supported by Reference Libraries

Natural products are an indispensable source for drug discovery. The major challenge for exploiting this evolutionary optimized pool of potential lead structures is the fast and reliable recognition of known compounds, i. e. dereplication. This task is essential for the discovery process i...

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Bibliographic Details
Main Authors: Jens Bitzer, Bärbel Köpcke, Marc Stadler, Veronika Hellwig, Yu-Ming Ju, Stephan Seip, Thomas Henkel
Format: Article
Language:deu
Published: Swiss Chemical Society 2007-06-01
Series:CHIMIA
Subjects:
Dereplication
Multidetector hplc
Natural products
Nmr
Secondary metabolites
Tandem mass spectrometry
Online Access:https://chimia.ch/chimia/article/view/4335

Internet

https://chimia.ch/chimia/article/view/4335

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