A-site residues move independently from P-site residues in all-atom molecular dynamics simulations of the 70S bacterial ribosome.

The ribosome is a large macromolecular machine, and correlated motion between residues is necessary for coordinating function across multiple protein and RNA chains. We ran two all-atom, explicit solvent molecular dynamics simulations of the bacterial ribosome and calculated correlated motion betwee...

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Bibliographic Details
Main Authors: Relly Brandman, Yigal Brandman, Vijay S Pande
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3250440?pdf=render