Dynamic Assessment of Tissue and Plasma <i>EGFR</i>-Activating and T790M Mutations with Droplet Digital PCR Assays for Monitoring Response and Resistance in Non-Small Cell Lung Cancers Treated with EGFR-TKIs

Dynamic Assessment of Tissue and Plasma <i>EGFR</i>-Activating and T790M Mutations with Droplet Digital PCR Assays for Monitoring Response and Resistance in Non-Small Cell Lung Cancers Treated with EGFR-TKIs

Assessing tumor <i>EGFR</i> mutation status is necessary for the proper management of patients with advanced non–small cell lung cancer (NSCLC). We evaluated the impact of dynamic analyses of the plasma and tissue <i>EGFR</i> mutation using ultra-sensitive droplet digital PCR...

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Bibliographic Details
Main Authors: Hsiang-Ling Ho, Fang-Yu Wang, Chi-Lu Chiang, Chun-Ming Tsai, Chao-Hua Chiu, Teh-Ying Chou
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
<i>EGFR</i> mutation
droplet digital PCR assays
EGFR-TKIs
circulating cell-free DNA
resistance mechanisms
Online Access:https://www.mdpi.com/1422-0067/23/19/11353

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https://www.mdpi.com/1422-0067/23/19/11353

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