Structural Basis for LMO2-Driven Recruitment of the SCL:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets

Structural Basis for LMO2-Driven Recruitment of the SCL:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets

Cell fate is governed by combinatorial actions of transcriptional regulators assembling into multiprotein complexes. However, the molecular details of how these complexes form are poorly understood. One such complex, which contains the basic-helix-loop-helix heterodimer SCL:E47 and bridging proteins...

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Bibliographic Details
Main Authors: Kamel El Omari, Sarah J. Hoosdally, Kapil Tuladhar, Dimple Karia, Elisa Hall-Ponselé, Olga Platonova, Paresh Vyas, Roger Patient, Catherine Porcher, Erika J. Mancini
Format: Article
Language:English
Published: Elsevier 2013-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713002866

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http://www.sciencedirect.com/science/article/pii/S2211124713002866

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