Bone marrow-targetable Green Tea Catechin-Based Micellar Nanocomplex for synergistic therapy of Acute myeloid leukemia

Bone marrow-targetable Green Tea Catechin-Based Micellar Nanocomplex for synergistic therapy of Acute myeloid leukemia

Abstract Background Currently available anti-leukemia drugs have shown limited success in the treatment of acute myeloid leukemia (AML) due to their poor access to bone marrow niche supporting leukemic cell proliferation. Results Herein, we report a bone marrow-targetable green tea catechin-based mi...

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Bibliographic Details
Main Authors: Ki Hyun Bae, Fritz Lai, Jamie Mong, Akiko Niibori-Nambu, Kiat Hwa Chan, Zhisheng Her, Motomi Osato, Min-Han Tan, Qingfeng Chen, Motoichi Kurisawa
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Journal of Nanobiotechnology
Subjects:
Bone marrow
Targeting
Sorafenib
Micellar nanocomplex
Leukemia
Online Access:https://doi.org/10.1186/s12951-022-01683-4

Internet

https://doi.org/10.1186/s12951-022-01683-4

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