Rhizoma Gastrodiae Water Extract Modulates the Gut Microbiota and Pathological Changes of P-TauThr231 to Protect Against Cognitive Impairment in Mice

Rhizoma Gastrodiae Water Extract Modulates the Gut Microbiota and Pathological Changes of P-TauThr231 to Protect Against Cognitive Impairment in Mice

Gastrodiae Rhizoma and its active constituents are known to exhibit neuroprotective effects in Alzheimer’s disease (AD). However, the effect of Rhizoma Gastrodiae water extract (WERG) on AD and the detailed mechanism of action remain unclear. In this study, the mechanism of action of WERG was invest...

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Bibliographic Details
Main Authors: Wenbin Zhao, Jianhui Wang, Maria Latta, Chenyu Wang, Yuheng Liu, Wantong Ma, Zhongkun Zhou, Shujian Hu, Peng Chen, Yingqian Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
Rhizoma Gastrodiae water extract
Alzheimer’s disease
P-Tau protein
gut microbiota
Lactobacillus johnsonii
Lactobacillus murinus
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.903659/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.903659/full

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