The inhibition of Wnt signaling attenuates RANKL-induced osteoclastogenic macrophage activation

Abdominal aortic aneurysms (AAAs) have been linked to the activation of osteoclastogenic macrophages. Reports have suggested that Wnt signaling has a dual effect of proliferation and differentiation during osteoclastogenesis. The Wnt/β-Catenin pathway is a critical regulator of cell pluripotency, ce...

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Bibliographic Details
Main Authors: Dai Yamanouchi, Kimihiro Igari
Format: Article
Language:English
Published: Bioscientifica 2023-07-01
Series:Vascular Biology
Subjects:
Online Access:https://vb.bioscientifica.com/view/journals/vb/5/1/VB-23-0007.xml