Immunogenicity of a Recombinant Gonadotropin-releasing Hormone Associated to the B Subunit of Escherichia coli Heat-labile Enterotoxin Expressed in Pichia pastoris and Escherichia coli Platforms

Immunogenicity of a Recombinant Gonadotropin-releasing Hormone Associated to the B Subunit of Escherichia coli Heat-labile Enterotoxin Expressed in Pichia pastoris and Escherichia coli Platforms

Abstract Gonadotropin-releasing hormone (GnRH) is one of the main targets for the development of immunocontraceptives vaccines. The aim of this study was to clone and express the recombinant GnRH fused to the B subunit of Escherichia coli heat-labile enterotoxin (LTB) molecule in Pichia pastoris and...

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Bibliographic Details
Main Authors: Lívia Budziarek Eslabão, Neida Lucia Conrad, Pedro Machado Medeiros de Albuquerque, Rodrigo Casquero Cunha, Antônio Sérgio Varela Junior, Fábio Pereira Leivas Leite
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2021-11-01
Series:Brazilian Archives of Biology and Technology
Subjects:
recombinant vaccine
contraception
GnRH
Pichia pastoris
Escherichia coli
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132021000100218&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132021000100218&tlng=en

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